In July 1947, the Sporthochschule Köln resumed the investigation that the Deutschen Hochschule für Leibesübungen had to end in 1935 because of its closure. In collaboration with the Universitär Krankenhaus Köln, Professor Hugo Wilhelm Knipping (1895-1984) started a research center for ergospirometry in 1949.
Parallel to this, a sports physiological lab was created.
The company of German instrument builder Albert Dargatz (1857-1941) from Hamburg built the first device that could measure an oxygen consumption of at least 3 L/min.
The device was used for the first time at the Sporthochschule Köln by the two doctorate students Norbert W. Tietz (1926-) and Wildor Hollmann (1925-), who carried out the first German ergospirometry tests.
In the article 'Normal Respiratory and Circulatory Pathways of Adaptation in Exercise' from 'The Journal of Clinical Investigation' of 1949, American cardiologist Robert A. Bruce (1916-2004) described running technology on a motor-driven treadmill, which regulates of the patient's activity for clinical applications.
The Collins Benedict-Roth Metabolise device from 1949.
Swiss-American physiologist Hans H. Hecht (1913-1971) from the University of Utah College of Medicine in Salt Lake City reported his experience with the anoxia test and claimed 90% sensitivity in coronary diseases. He stressed the important fact that pain is an unreliable endpoint that accompanies ischemia only in 50% of cases. He also pointed out that changes of the ST segment associated with anoxemia may not be present if previous myocardial necrosis has occurred.