A research team from the Netherlands and Denmark performed a prospective cohort study between 2009 and 2010 which included sixty CHF patients. The program consisted of exercise sessions at 6 days/week. Total training time of aerobic exercises increased incrementally every other week without changing exercise intensity. Resistance exercise training consisted of 8 exercises with a durable resistance band. Guidance consisted of a step-down approach from in-hospital to home-based training. Cardio-pulmonary exercise tests were performed at baseline, 3, 6 and 12 months. Subsequently patients were propensity score matched on a 1:2 ratio with 117 controls from a CHF-registry of patients from the same clinic receiving usual out-patient care and the incidence of all-cause mortality was compared between both groups.
Baseline VO2 peak was 15.0 ml/min/kg and significantly elevated at 3 months, 6 months and 12 months. During 8 years of follow-up 23 patients of the program died versus 63 patients of the control group.
Med Sci Sports Exerc. 2018 Jun 21. doi: 10.1249/MSS.0000000000001688.?